New research has found that high levels of niacin, a B vitamin, could increase the risk of heart disease by causing inflammation and damaging blood vessels. The study, published in Nature Medicine, discovered that excessive amounts of niacin could pose a risk, even though it is present in many foods. The recommended daily allowance of niacin is 16mg for men and 14mg for non-pregnant women. The study also revealed that about 1 in 4 Americans have higher than recommended levels of niacin. The research found a substance in the blood that is only produced when there is excess niacin, and this can predict the risk of heart attack, stroke, and death. The discovery creates a new pathway to understanding heart disease and could lead to the development of medications to reduce blood vessel inflammation. These findings may influence dietary recommendations for niacin and present promising opportunities for future research.
