Wednesday, October 22, 2025

Understanding the Effects of Psilocybin on Brain Plasticity: Exploring the Connection between Drugs and Neuroplasticity

Share

New Study Shows How Psychedelics Affect the Brain

A recent study published in the journal Nature has shed light on how psychedelic drugs, such as psilocybin found in magic mushrooms, affect the brain. The study involved seven participants, including Dr. Nico Dosenbach, who ingested a high dose of psilocybin before undergoing brain scans.

The results of the study suggest that psychedelic drugs disrupt specific brain networks, particularly those associated with spatial awareness, time perception, and self-awareness. Dr. Petros Petridis of New York University’s Langone Center for Psychedelic Medicine, who co-authored an editorial on the study, explained that the drugs enhance the brain’s ability to adapt and change, known as plasticity.

Dr. Joshua Siegel, the lead author of the study, pointed out that the disrupted brain networks are responsible for the plasticity effects of psychedelics. This finding could explain why these drugs show promise in treating addiction and depression.

Participants described their experiences under the influence of psilocybin as mind-bending and enlightening. Dr. Dosenbach likened his trip to “riding brain waves” and even feeling like a renowned neuroscientist, Dr. Marcus Raichle.

The study’s detailed brain scans revealed that psilocybin caused significant changes in specific brain networks, leading to a state of enhanced plasticity that persisted for weeks. The default mode network, associated with self-referential memory, was particularly affected.

While the study highlights the potential therapeutic benefits of psychedelics, experts caution that these drugs have risks. However, they also acknowledge the drugs’ unique ability to help patients recognize their capacity for change and recovery.

In conclusion, the study provides valuable insights into how psychedelic drugs impact the brain and offers hope for their future use in psychiatric treatment.


Vocabulary List:

  1. Psychedelic /ˌsaɪ.kəˈdɛl.ɪk/ (adjective): Relating to or denoting drugs that produce altered states of perception and consciousness.
  2. Plasticity /plæsˈtɪs.ɪ.ti/ (noun): The ability of the brain to change and adapt as a result of experience.
  3. Network /ˈnɛt.wɜrk/ (noun): A group or system of interconnected people or things.
  4. Perception /pərˈsɛpʃən/ (noun): The way in which something is regarded understood or interpreted.
  5. Disrupt /dɪsˈrʌpt/ (verb): To interrupt the normal progress or activity of something.
  6. Therapeutic /ˌθɛrəˈpjuːtɪk/ (adjective): Relating to the healing of disease or having a beneficial effect on health.

How much do you know?

What is the main focus of the recent study published in the journal Nature?
Effects of caffeine on the brain
Effects of psychedelic drugs on the brain
Effects of exercise on the brain
Effects of meditation on the brain
Which specific brain networks are disrupted by psychedelic drugs according to the study?
Emotional processing networks
Language processing networks
Spatial awareness time perception and self-awareness networks
Motor control networks
Who is mentioned as feeling like a renowned neuroscientist during the study?
Dr. Nico Dosenbach
Dr. Petros Petridis
Dr. Joshua Siegel
Dr. Marcus Raichle
What effect do psychedelic drugs have on the brain networks as explained by Dr. Joshua Siegel?
They stabilize the networks
They disrupt the networks
They magnify the networks
They reroute the networks
Which brain network associated with memory was particularly affected by psilocybin in the study?
Executive control network
Default mode network
Visual network
Auditory network
What is one potential application of psychedelic drugs mentioned in the study?
Improving math skills
Treating addiction and depression
Enhancing athletic performance
Boosting creativity
This question is required

Read more

Local News