Researchers assessed the efficacy of 17 drugs for treating migraines
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An extensive review of clinical trials suggests that underutilized triptan drugs, which are specifically formulated for migraine treatment, may be more effective in managing migraine symptoms compared to newer, more expensive medications.
Research indicates that despite their efficacy, triptans are used in less than 22 percent of migraine cases. Therefore, experts recommend considering these cost-effective triptans as a primary treatment option for migraine relief, especially for patients without contraindications like cardiovascular diseases.
Triptans like sumatriptan and eletriptan, available as off-brand or generic tablets, have shown promising results. On the other hand, newer drugs called ditans and gepants, designed to avoid cardiovascular risks associated with triptans, have entered the market at a high cost.
Various studies have compared the effectiveness of these drugs, revealing that eletriptan and ibuprofen are among the most effective options for managing migraine pain over a 24-hour period. In contrast, newer drugs like lasmiditan, rimegepant, and ubrogepant have shown no significant advantage over common pain relievers like paracetamol and NSAIDs.
In conclusion, while triptans are recommended for certain individuals, the choice of treatment for migraines should be personalized, considering individual needs and medical history.
Migraine management is a complex matter that requires a tailored approach to ensure the best outcomes for each patient.
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Vocabulary List:
- Efficacy /ˈɛfɪkəsi/ (noun): The ability to produce a desired or intended result.
- Underutilized /ˌʌndərˈjuːtɪlaɪzd/ (adjective): Not put to use to the fullest extent.
- Contraindications /ˌkɒntrəˌɪndɪˈkeɪʃənz/ (noun): Specific situations where a drug should not be used.
- Formulated /ˈfɔːrmjuleɪtɪd/ (verb): Created or devised a method or plan.
- Tailored /ˈteɪlərd/ (verb): Adapted or adjusted for a specific purpose or individual.
- Management /ˈmænɪdʒmənt/ (noun): The process of dealing with and controlling things or people.
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