Christina Applegate has been dealing with multiple sclerosis for the past three years, and it has been a challenging journey for her. She has been hospitalized over 30 times due to symptoms like vomiting, diarrhea, and pain. Applegate has undergone numerous tests and procedures to understand the root cause of her health issues.
Recently, she has discovered a possible connection between MS and motility issues affecting the organs. This has led her to advise others with similar MS side effects to discuss this possibility with their doctors. She has also shared her personal struggles, such as experiencing vomiting when needing to go to the bathroom.
Despite her doctor’s initial disbelief in the correlation between MS and her symptoms, Applegate is determined to explore further by undergoing a colonoscopy. She openly talks about the challenges she faces, including the unpleasant experience of having both diarrhea and vomiting simultaneously.
Through her podcast “MeSsy” with Jamie-Lynn Sigler, who also has MS, Applegate aims to raise awareness about the autoimmune disease and provide support to others dealing with similar health issues. Their candid discussions shed light on the different ways MS can manifest and the emotional toll it takes on individuals.




