Tuesday, April 7, 2026

Scientists Explore Genes of Woman Who Lacked Pain Sensation

Jo Cameron from Scotland lives without feeling pain. Most of her life, she thought this was normal for her. Even after surgeries, she felt no pain. Doctors began to study her after they saw this unusual situation.

In 2019, researchers found a gene called FAAH-OUT. This gene is very special. Jo is one of only two people in the world with changes in this gene. Now in her late 70s, scientists continue to learn from her case.

Jo told reporters she did not know her lack of pain was strange. She only realised something was different when she was 65. She felt happy but did not know her body worked differently.

Before studying Jo, scientists thought the FAAH-OUT gene was useless. Now, they see it helps control pain and mood. A new study showed that this gene could help with healing wounds and mood disorders.

Scientists want to use this knowledge to create better medicines. They hope their work will help many patients in the future.

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Vocabulary List:
6 words · tap to reveal
ON

Accent

gene/dʒin/noun
part of cells that tells how you grow

surgeries/ˈsɝːdʒəriz/noun
medical operations to fix or remove problems

unusual/ənˈjuːʒuəl/adjective
not normal and different from most things

researchers/rɪˈsɝːtʃərz/noun
people who study subjects to find new facts

control/kənˈtroʊl/verb
to make something happen or not happen

healing/ˈhiːlɪŋ/noun
making a body part become healthy again

How much do you know?

What is the name of the special gene that Jo Cameron has?
FAAH-OUT
GENE-X
PAIN-LESS
MUT-1
At what age did Jo Cameron realize her lack of pain was unusual?
55
60
65
70
How many people in the world are known to have changes in the FAAH-OUT gene?
1
2
3
4
What did researchers initially think of the FAAH-OUT gene?
Useful
Useless
Harmful
Dangerous
What is one of the potential benefits of the FAAH-OUT gene discovered by scientists?
Memory enhancement
Better pain control
Increased risk of diseases
Weight loss
In which country does Jo Cameron live?
England
Scotland
Wales
Northern Ireland
Jo Cameron has felt pain after surgeries.
FAAH-OUT gene was previously thought to be useless.
Jo Cameron is in her 50s.
Researchers want to use the knowledge gained from Jo Cameron to improve medicine.
Jo only realized her body worked differently after turning 70.
Jo Cameron is one of three people with changes in the FAAH-OUT gene.
Jo Cameron lives without feeling pain.
The FAAH-OUT gene is said to help control pain and .
Jo Cameron was studied by doctors after they noticed her situation.
She only realized something was different about her body when she was .
Scientists hope their work will lead to better for patients.
Jo Cameron was born in and still continues to share her story.
This question is required

Test Your Understanding

Start Quiz
Vocabulary List:
6 words · tap to reveal
ON
Accent
gene/dʒin/noun
part of cells that tells how you grow
surgeries/ˈsɝːdʒəriz/noun
medical operations to fix or remove problems
unusual/ənˈjuːʒuəl/adjective
not normal and different from most things
researchers/rɪˈsɝːtʃərz/noun
people who study subjects to find new facts
control/kənˈtroʊl/verb
to make something happen or not happen
healing/ˈhiːlɪŋ/noun
making a body part become healthy again

How much do you know?

What is the name of the special gene that Jo Cameron has?
FAAH-OUT
GENE-X
PAIN-LESS
MUT-1
At what age did Jo Cameron realize her lack of pain was unusual?
55
60
65
70
How many people in the world are known to have changes in the FAAH-OUT gene?
1
2
3
4
What did researchers initially think of the FAAH-OUT gene?
Useful
Useless
Harmful
Dangerous
What is one of the potential benefits of the FAAH-OUT gene discovered by scientists?
Memory enhancement
Better pain control
Increased risk of diseases
Weight loss
In which country does Jo Cameron live?
England
Scotland
Wales
Northern Ireland
Jo Cameron has felt pain after surgeries.
FAAH-OUT gene was previously thought to be useless.
Jo Cameron is in her 50s.
Researchers want to use the knowledge gained from Jo Cameron to improve medicine.
Jo only realized her body worked differently after turning 70.
Jo Cameron is one of three people with changes in the FAAH-OUT gene.
Jo Cameron lives without feeling pain.
The FAAH-OUT gene is said to help control pain and .
Jo Cameron was studied by doctors after they noticed her situation.
She only realized something was different about her body when she was .
Scientists hope their work will lead to better for patients.
Jo Cameron was born in and still continues to share her story.
This question is required

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